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Research Programs

A Message from Nina Gentile, MD

Professor, Department of Emergency Medicine
Vice Chair of Research, Department of Emergency Medicine 

A wide variety of clinical research activities are conducted in the Department of Emergency Medicine at the Lewis Katz School of Medicine, and they reflect the diverse interests of our faculty and residents. 

Medical students and resident physicians are invited to participate in research projects under the Mentorship of Emergency Medicine faculty. Opportunities for interdepartmental collaborative research efforts with other clinical departments and translational research with basic science research. Resources, such as biostatistical, are available to support student and resident research both in the Department and throughout the School of Medicine and Health Sciences Campus.

The Department of Emergency Medicine has active research programs in emergency ultrasound; acute neurological illness and injury such as acute stroke, status epilepticus, and traumatic brain injury; critical illness; and emerging infectious diseases. The Multiple Emergency Medicine faculty have been awarded federal grants. The Department of Emergency Medicine conducts federally funded, industry sponsored, and investigator-initiated trials.

I invite all residency candidates to contact me (ngentile@temple.edu) to discuss Emergency Medicine research opportunities at Temple.
 

Research Networks

The Department of Emergency Medicine at Temple University is a key Clinical Research Hub within the NIH-funded SIREN Network, connecting academic and community hospitals. SIREN focuses on improving outcomes for patients facing neurologic, cardiac, respiratory, and hematologic emergencies by testing time-sensitive treatments, especially for stroke care. Temple serves as the SIREN hub for Philadelphia, collaborating with urban and rural hospitals to optimize stroke interventions like thrombolytics and thrombectomy. Temple also participates in other networks like EMERGEncy ID NET, which focuses on emerging infectious diseases in collaboration with the CDC, and StrokeNet, advancing stroke treatment and prevention across 27 centers and over 500 U.S. hospitals, with international partnerships.

Pathway to Clinical Trials
  • Explore ongoing emergency medicine clinical trials focused on improving outcomes for cardiac arrest, stroke, pneumonia, and other critical conditions. Our research includes studies like ICECAP, FASTEST, ARREST Pneumonia, LIBREXIA, and SISTER, investigating new treatments and interventions to enhance patient care. Learn more about these trials and their impact on medical advancements.
Investigator Initiated Clinical Research
  • Residents critically analyze the latest medical literature, contribute to departmental best practices, and engage in performance improvement projects that may lead to publications, abstracts, and posters in emergency medicine.
Hands-On Emergency Medicine Research: Summer Work Study for First-Year Medical students.
  • This is a hands-on clinical research opportunity for first-year medical students interested in emergency medicine. Through this program, first-year medical students gain insight into what it’s like to work in the emergency room setting, apply their knowledge from the classroom into a clinical research space (i.e. history taking, physical examination, patient interaction, presenting cases), and learn about the role of physicians in clinical research (i.e., adverse event assessment and reporting).
From Undergrad to Postgrad: Research Awaits
  • The journey from undergraduate to postgraduate studies marks an exciting new chapter in a researcher’s academic and professional development at Temple’s Emergency Department. Undergraduate and Postgraduate research provides the chance to explore specialized areas of emergency medicine, contribute to innovative discoveries, and improve patient care. With access to advanced resources and guidance from experienced mentors, students can deepen their knowledge, develop critical research skills, and actively shape the future of healthcare. This transition opens doors to meaningful research opportunities that have the potential to transform emergency care practices and public health outcomes.
Advancing Emergency Care: Key Research in Epidemiology and Ultrasound Technology
  • At Temple Emergency Department Research, we are dedicated to exploring critical health trends in epidemiology and innovative ultrasound technologies to enhance patient care. Our epidemiology research tackles rising chronic conditions like diabetes and heart disease, as well as infectious diseases, using tools such as big data and genomics to develop personalized treatment strategies. We also examine health disparities and social factors that influence outcomes, aiming to improve community health. In parallel, our frontline ultrasound research, led by Dr. Thomas Costantino, focuses on improving diagnostic accuracy and patient care through ultrasound-guided procedures, renal ultrasound for kidney stones, and vascular access techniques. Residents and students are encouraged to participate in these pioneering studies, advancing point-of-care ultrasound (POCUS) applications in emergency medicine.
Breakthroughs in Addiction Medicine Research
  • Temple's Emergency Department is leading the way in Addiction Medicine Research, pioneering new approaches to understanding and treating substance use disorders. With advancements in neuroscience, pharmacology, and behavioral therapy, researchers are uncovering innovative treatments that provide hope for lasting recovery. These breakthroughs enhance treatment options, aid in addiction prevention, reduce stigma, and allow for more personalized care. As research progresses, we are getting closer to effective solutions that empower individuals to overcome addiction and live healthier, more fulfilling lives.

Research Staff

Research Manager: 
  • Katen McCully, MPH
Core Research Faculty 
Clinical Research Nurse: 
  • Hannah Reimer, RN, BSN
  • Mark Kieh, RN, BSN
Research Coordinator:
  • Maria Casanova, MD
  • Fatme Chaloub, BS
  • Austin Hsin, MPH
Regulatory Coordinator: 
  • Mary Ajibolade, BS
Grants Administrator: 
  • Hillary Richards, MSc, MA