In This Section

Clinical Research and Trials

Cardiology

Rene Alvarez, MD (Cardiology) – Sponsor: Teva Pharmaceuticals
“Safety Study of Allogeneic Mesenchymal Precursor Cells In Patients with Chronic Heart Failure Due to Left Ventricular Systolic Dysfunction of Either Ischemic”

Jeffrey Arkles, MD (Cardiology) – Sponsor: Biotronik
“Sentus QP – Extended CRT Evaluation with Quadripolar Left Ventricular Leads IDE# G150147”

Riyaz Bashir, MD (Cardiology) – Sponsor: Washington University
“Acute Venous Thrombosis: Thrombus Removal with Adjunctive Catheter-Directed Thrombolysis”

Riyaz Bashir, MD (Cardiology) – Sponsor: AstraZeneca
“Ticagrelor with Clopidogrel Treatment on the Risk of Cardiovascular Death, Myocardial Infarction and Isahaemic Stroke in Patients with Established Peripheral Artery Disease”

Riyaz Bashir, MD (Cardiology) – Sponsor: Sanofi-aventis U.S. Inc.
“On the Occurrence of Cardiovascular Events in Patients Who Have Recently Experienced an Acute Coronary Syndrome”

Riyaz Bashir, MD (Cardiology) – Sponsor: Cook Research, Inc.
“Evaluation of Zilver Vena Venous Stent in the Treatment of Symptomatic Iliofemerol Venous Outflow Obstruction (Vivo Clinical Study)”

Riyaz Bashir, MD (Cardiology) – Sponsor: Bayer Healthcare
“An international, multicenter, randomized, double-blind, placebo-controlled phase 3 trial investigating the efficacy and safety of rivaroxaban to reduce the risk of major thrombotic vascular events in patients with symptomatic peripheral artery disease undergoing lower extremity revascularization procedures. VOYAGER PAD”

Riyaz Bashir, MD (Cardiology) – Sponsor: Dalcor Pharma UK Ltd.
“A Phase III, Double-Blind, Randomized Placebo-Controlled Study to Evaluate the Effects of Dalcetrapib on Cardiovascular (CV) Risk in a Genetically Defined Population with a Recent Acute Coronary Syndrome (ACS)”

Meredith Brisco, MD (Cardiology) – Sponsor: National Institutes of Health
“Determining Mechanisms of Renal Dysfunction after Left Ventricular Assist Device”

Joshua Cooper, MD (Cardiology) – Sponsor: Boston Scientific
“S-ICD System Post Approval Study”

Joshua Cooper, MD (Cardiology) – Sponsor: Medtronic Inc.
“World-Wide Randomized Antibiotic Envelope Infection Prevention Trial (WRAP-IT)”

Daniel Dries, MD (Cardiology) – Sponsor: University of Pittsburgh
“Genomic Analysis of Enhanced Response to Heart Failure Therapy in African-Americans - GRAHF2”

Arthur Feldman, MD (Cardiology) – Sponsor: University of Pittsburgh
“Genomic Analysis of Enhanced Response to Heart Failure Therapy in African-Americans”

Paul Forfia, MD (Cardiology) – Sponsor: Bayer Healthcare LLC
“U.S. CTEPH Registry”

Brian O’Murchu, MD (Cardiology) – Sponsor: Boston Scientific
“EVOLVE II: A Prospective Multicenter Trial to Assess the Safety and Effectiveness of the SYNERGY Everolimus-Eluting Platinum Chromium Coronary Stent System for the Treatment of Atherosclerotic Lesion(s)”

Brian O’Neill, MD (Cardiology) – Sponsor: Evalve, Inc.
“COAPT MitraClip Percutaneous Therapy for High Surgical Risk Patients”

Brian O’Neill, MD (Cardiology) – Sponsor: Cardiac Assist, Inc.
“Tandem heart Experiences and Methods”

Brian O’Neill, MD (Cardiology) – Sponsor: Edwards Life Sciences, LLC
“Heterotopic Implantation of the Edwards-Sapien Xt Trans catheter Valve in the Inferior Vena Cava for the Treatment of Severe Tricuspid Regurgitation”

Lynn Punnoose, MD (Cardiology) – Sponsor: Card DX
“Outcomes AlloMap Registry (OAR) study and sub study: Utility of Donor-Derived Cell-free DNA in Association with Gene-Expression Profiling (AlloMap) in Heart Transplant Recipients (D-OAR) PROTOCOL NO.: SN-C-00003 & SN-C-00004”

Endocrinology

Ajaykumar Rao, MD (Endocrinology) – Sponsor: Novo Nordisk
“Effects of Liraglutide on Endoplasmic Reticulum (ER) Stress in Obese Subjects with Type 2 Diabetes”

Ajaykumar Rao, MD (Endocrinology) - Sponsor: Fox Chase Cancer Center
“A Biobehavioral Model of Diabetes Risk in Chinese Immigrants”

Ajaykumar Rao, MD (Endocrinology) – Sponsor: Bristol-Myers Squibb
“A multi-center randomized double blind placebo controlled parallel group phase 3 study to evaluate the efficacy and safety of Dapagliflozin as an add on to insulin therapy in subjects with type 1 diabetes melitius study two.”

Daniel Rubin, MD (Endocrinology) - Sponsor: National Institutes of Health
“Predicting And Preventing Hospital Readmission In Patients With Diabetes And Cvd”

Daniel Rubin, MD (Endocrinology) – Sponsor: Boehringer Ingelheim Pharmaceutical
“A Multicentre, International, Randomized, Parallel Group, Double-Blind Study to Evaluate Cardiovascular Safety of Linagliptin Versus Glimepiride in Patients with Type 2 Diabetes Mellitus at High Cardiovascular Risk. The CAROLINA Trial.”

Daniel Rubin, MD (Endocrinology) – Sponsor: Emory University
“Randomized Controlled Trial on the Efficacy of Sitagliptin Therapy for the Inpatient Management of General Medicine and Surgery Patients with Type 2 Diabetes”

Daniel Rubin, MD (Endocrinology) – Sponsor: Emory University
“A Randomized Controlled Pilot Trial on the Safety and Efficacy of Exenatide (Byetta) Therapy for the Inpatient Management of General Medicine and Surgery Patients with Type 2 Diabetes”

Cherie Vaz, MD (Endocrinology) - Sponsor: Obesity Treatment Foundation
“Non Exercise Activity Thermogenesis and Heart Rate Variability in Obese Subjects”

Cherie Vaz, MD (Endocrinology) – Sponsor: Boehringer-Ingelheim Pharmaceutical
“A Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Efficacy and Safety Study of Empagliflozin (10 Mg, 25 Mg) Administered Orally, Once Daily Over 24 Weeks in Hypertensive Black African American Patients with Type 2 Diabetes Mellitus”

Gastroenterology

Adam Ehrlich, MD (Gastroenterology) – Sponsor: Janssen Research & Development, LLC
“A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Protocol to Evaluate the Safety and Efficacy of Ustekinumab Induction and Maintenance Therapy in Subjects with Moderately to Severely Active Ulcerative Colitis”

Jennifer Maranki, MD (Gastroenterology) – Sponsor: Boston Scientific
“A Prospective Multi-Center Registry Using Plastic Pancreatic Stents for Short-Term Drainage of the Pancreatic Duct”

Jennifer Maranki, MD (Gastroenterology) – Sponsor: Boston Scientific
“Mid-Atlantic Research Group single-operator cholangioscopic assessment of biliary strictures: the SOCABS pilot”

Henry Parkman, MD (Gastroenterology)  - Sponsor: National Institutes of Health
“Temple University Gastroparesis Clinical Center” (U01)

Henry Parkman, MD (Gastroenterology) - Sponsor: Georgia Regents University
“Islet Autoantibodies in T2DM Patients with Gastroparesis”

Henry Parkman, MD (Gastroenterology) – Sponsor: Prostraken, Inc.
“Use of Sancuso in Patients with Nausea and/or Vomiting from Gastroparesis: Open-Label Study”

Henry Parkman, MD (Gastroenterology) – Sponsor: Theravance, Inc.
“A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group. Phase 2 Study to Assess the Efficacy, Safety and Tolerability of Velusetrag for the Treatment of Diabetic or Idiopathic Gastroparesis”

Robin Rothstein, MD (Gastroenterology) – Sponsor: AbbVie, Inc.
“Long-Term Non-Interventional Registry to Access Safety and Effectiveness of HUMIRA in Patients with Moderately to Severely Active Ulcerative Colitis”

Ron Schey, MD (Gastroenterology) – Sponsor: Forest Research Institute
“An Open-Label, Multiple-Dose, Milk-Only Lactation Study in Lactating Women Receiving Linaclotide Therapeutically”

Ron Schey, MD (Gastroenterology) – Sponsor: Forest Research Institute
“An Open-label, Long-term Study to Assess the Immunogenicity of Linaclotide Administered Orally to Adult Patients with Irritable Bowel Syndrome with Constipation or Chronic Idiopathic Constipation (LIN-MD-10)”

Ron Schey, MD (Gastroenterology) – Sponsor: Synergy Pharmaceuticals
“Second Phase 3 Randomized, 12-Week, Double-Blind, Placebo-Controlled Study of the Safety and Efficacy of Plecanatide in Patients with Irritable Bowel Syndrome with Constipation (IBS-C)”

Ron Schey, MD (Gastroenterology) – Sponsor: AstraZeneca
“Movantik™ for Opioid-Related Esophageal Disorders”

Michael Smith, MD (Gastroenterology) – Sponsor: CDx Diagnostics
“WATS Registry”

General Internal Medicine

Sharon Herring, MD (General Internal Medicine) – Sponsor: American Beverage Association
“The Role of No-Calorie Sweetened Beverages within a Weight Loss Behavior Change Program and During Subsequent Weight Maintenance”

Sharon Herring, MD (Gastroenterology) – Sponsor: Novo Nordisk
“Efficacy and Safety of Oral Semaglutide Versus Empagliflozin in Subjects with Type 2 Diabetes Mellitus”

Sharon Herring, MD (General Internal Medicine) - Sponsor: Doris Duke Charitable Foundation
“The Influence of Postpartum Sleep Duration on Adiposity and Cardiometabolic Risk Factors in Urban, Low-Income Mothers”

Sharon Herring, MD (General Internal Medicine) - Sponsor: Health Resources and Services Admin
“Targeting Pregnancy-related Weight Gain to Reduce Disparities in Obesity: A Randomized Controlled Trial”

Sharon Herring, MD (General Internal Medicine) - Sponsor: National Institutes of Health
“Community-Based Obesity Treatment In African American Women After Childbirth” (R01)

Anuradha Paranjape, MD (General Internal Medicine) - Sponsor: University of Pittsburgh
“A P2ATH Towards A Learning Health System In The Mid-Atlantic Region”

Anuradha Paranjape, MD (General Internal Medicine) - Sponsor: Penn State Hershey Medical Center
“Integrating Patient-Centered Exercise Coaching Into Primary Care To Reduce Fragility Fracture”

Anuradha Paranjape, MD (General Internal Medicine) - Sponsor: University of Pittsburgh
“Aspirin Dosing: A Patient-Centric Trial Assessing Benefits and Long Term Effectiveness (ADAPTABLE)”

Anuradha Paranjape, MD (General Internal Medicine) - Sponsor: University of Pittsburgh
“PCORnet Bariatrics outcome study”

Anuradha Paranjape, MD (General Internal Medicine) - Sponsor: Pennsylvania State University
“A Patient-Centered PaTH to Addressing Diabetes: Impact of State Health Policies on Diabetes Outcomes and Disparities”

Gina Simoncini, MD (General Internal Medicine) – Sponsor: Gilead Sciences, Inc.
“Clinical Partnerships – HIV & HCV Screening Expansion Projects”

Ellen Tedaldi, MD (General Internal Medicine) – Sponsor: Institute for Clinical Research, Inc.
“Strategic Timing of Antiretroviral Therapy”

Ellen Tedaldi, MD (General Internal Medicine) – Sponsor: Cerner Corporation
“HIV Outpatient Study (HOPS)”

Ellen Tedaldi, MD (General Internal Medicine) - Sponsor: Philadelphia Dept. Of Public Health
“HIV Screening And Testing In Health Care Settings”

Ellen Tedaldi, MD (General Internal Medicine) - Sponsor: Philadelphia Dept. Of Public Health
“Care Services Case Management”

Ellen Tedaldi, MD (General Internal Medicine) - Sponsor: City of Philadelphia
“MAI Ambulatory Outpatient Medical Care Services”

Hematology

A.Koneti Rao, MD (Hematology) - Sponsor: National Institutes of Health
“Insights on Selected Procoagulation Markers and Outcomes in Stroke Trial (I-SPOT)” (U01)

A.Koneti Rao, MD (Hematology) – Sponsor: National Institutes of Health
“Human Platelet Defects in Transcription Factor RUNX1 Haplodeficiency” (R01)

A.Koneti Rao, MD (Hematology) – Sponsor: Dart NeuroScience, LLC
“The Effect of Dart Neuroscience's DNS-3379 and DNS-7801 Inhibitors and DNS-6288 on Platelet Aggregation and Secretion Responses in Human Platelets”

Hepatology

Abdullah Al-Osaimi, MD (Hepatology) – Sponsor: SC Liver Research Consortium
“HCV-01-11, Multicenter, Prospective Evaluation of the Beckman Coulter DxN HCV Viral Load Assay as an Aid in the Management of the HCV-Infected Individuals Undergoing Antiviral Therapy”

Abdullah Al-Osaimi, MD (Hepatology) – Sponsor: SC Liver Research Consortium
“Multicenter, Prospective Evaluation of the Beckman Coulter DxN HBV Assay as an Aid in the Management of HBV-infected Individuals Undergoing Antiviral Therapy”

Abdullah Al-Osaimi, MD (Hepatology) – Sponsor: SC Liver Research Consortium
“Collection of Blood Specimens from Subjects Infected with Chronic Hepatitis C (Genotypes 2 and 3) and Treated with Sofosbuvir Plus Ribavirin”

Abdullah Al-Osaimi, MD (Hepatology) – Sponsor: Conatus Pharmaceuticals
“A Multicenter, Randomized, Double-Blind, Placebo-controlled Trial of Emricasan (IDN-6556), an Oral Caspase Inhibitor, in Subjects with Non-alcoholic Steatohepatitis (NASH) Fibrosis. Protocol no. IDN-6556-12”

Infectious Diseases

Jeffrey Jacobson, MD (Infectious Disease) – Sponsor: TaiMed Biologics
“A Phase 1, Randomized, Double-Blinded, Placebo-Controlled, Sequential Single Dose Escalation Study of the Safety, Tolerability and Pharmacokinetics of Subcutaneously and Intramuscularly Administered TMB-607 in HIV-Negative Volunteers”

Jeffrey Jacobson, MD (Infectious Disease) – Sponsor: Massachusetts General Hospital (flow-through NHLBI)
“Randomized Trial to Prevent Vascular Events in HIV – REPRIEVE (A5332)”

Jeffrey Jacobson, MD (Infectious Diseases) - Sponsor: University of Pennsylvania
“The Florida Node Alliance of the National Drug Abuse Treatment Clinical Trials Network (CTN-0064)”

Nephrology

Joseph Benjamin, MD (Nephrology) – Sponsor: Abbvie, Inc.
“A Randomized, Multicountry, Multicenter, Double-Blind, Parallel, Placebo-Controlled Study of the Effects of Atrasentan on Renal Outcomes”

Crystal Gadegbeku, MD (Nephrology) – Sponsor: Akebia Therapeutics
“Phase 3, Randomized, Open-Label, Active-Controlled Study Evaluating the Efficacy and Safety of Oral Vadadustat for the Maintenance Treatment of Anemia in Subjects with Non-Dialysis-Dependent Chronic Kidney Disease (NDD-CKD) (PRO2TECT - CONVERSION)”

Crystal Gadegbeku, MD (Nephrology) – Sponsor: Case Western University
“Systolic Blood Pressure Intervention Trial – SPRINT”

Crystal Gadegbeku, MD (Nephrology) – Sponsor: University of Michigan
“Nephrotic Syndrome Rare Disease Clinical Research Network (NEPTUNE II)”

Crystal Gadegbeku, MD (Nephrology) – Sponsor: University of Pennsylvania
“Cure Glomerulonephropathy – Supplement (Nephcure)”

Crystal Gadegbeku, MD (Nephrology) - Sponsor: University of Michigan
“Clinical Phenotyping Resource and Biobank Core (C-PROBE)”

Crystal Gadegbeku, MD (Nephrology) - Sponsor: University of Pennsylvania
“Primary Outcomes in Glomerulonephritis Study (CureGN/ Progress)”

Crystal Gadegbeku, MD (Nephrology) - Sponsor: University of Michigan
“Nephrotic Syndrome Rare Disease Clinical Research Network (NEPTUNE)”

Duncan Johnstone, MD (Nephrology) – Sponsor: Retrophin, Inc.
“Efficacy and Safety of RE-021, A Dual Endothelin Receptor and Angiotensin Receptor Blocker, In Patients with Focal Segmental Glomerulosclerosis (FSGS): A Randomized, Double-Blind, Active-Control, Dose-Escalation Study”

Iris Lee, MD (Nephrology) – Sponsor: Human Genome Sciences, Inc.
“A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Belimumab Plus Standard of Care Versus Placebo Plus Standard of Care in Adult Subjects with Active Lupus Nephritis”

Iris Lee, MD (Nephrology) – Sponsor: University of Michigan
“To Assess the Association between Disease Specific Markers and Targets Pathways Associated with Inflammation and Tissue Injury Fibrosis in Lupus Nephritis (BIPI-LN)”

Iris Lee, MD (Nephrology) – Sponsor: Regents University of California
“PEARL Phase 1 extended”

Jean Lee, MD (Nephrology) – Sponsor: Dialysis Clinic, Inc.
“A Phase 3, Open Label, Randomized, Active Controlled Study of the Efficiency and Safety of Roxadustat (FG-4592) in the Maintenance Treatment of Anemia in Subjects with End Stage Renal Disease (ESRD) on Stable Dialysis”

Rheumatology

Roberto Caricchio, MD (Rheumatology) – Sponsor: Resolve Therapeutics
“A Phase 2a, Double-Blind, Placebo Controlled Study of RSLV-132 in Subjects with Systemic Lupus Erythematosus (SLE)”

Roberto Caricchio, MD (Rheumatology) – Sponsor: AstraZeneca
“A Multicentre, Randomised, Double-blind, Placebo-Controlled, Phase 3 Study Evaluating the Efficacy and Safety of Two Doses of Anifrolumab in Adult Subjects with Active Systemic Lupus Erythematosus (AZ TULIP 1)”

Philip Cohen, MD (Rheumatology) – Sponsor: Janssen Research & Development, LLC
“Systemic Lupus Erythematosus Biomarker”