Michael Autieri, PhD
Director and Professor, Lemole Center for Integrated Lymphatics Research
Associate Director and Professor, Cardiovascular Research Center
Professor, Cardiovascular Sciences
Professor, Center for Metabolic Disease Research
Professor, Sol Sherry Thrombosis Research Center
Professor, Biomedical Education and Data Science
- Contact Information
-
- About Me
-
Research Interests
The long-term focus of our research program is the identification and characterization of proteins and pathways which play a role in regulation of vascular inflammation, with a current focus on the role of endogenous anti-inflammatory cytokines in this process. We have two distinct, but related areas of investigation: 1- inhibition of vascular occlusive diseases such as atherosclerosis, restenosis, and allograft vasculopathy, and; 2- promotion of angiogenesis to treat peripheral vascular disease. Currently, we are focusing on an endogenous anti-inflammatory cytokine termed IL-19 which: regulates macrophage polarity, macrophage and smooth muscle cell cholesterol homeostasis, smooth muscle and endothelial cell proliferation, and decreases inflammatory mRNA stability, suggesting that this cytokine may represent a therapeutic modality to treat vascular inflammatory diseases.
- Education, Training & Credentials
-
Educational Background
- PhD, Hahnemann University, Philadelphia, PA
- Publications
-
Digital Bibliography
Katz School of Medicine News
