Xiao-Feng Yang, MD, PhD, FAHA

Research Interests

1. Vascular immunology and atherosclerosis. Dr. Yang’s laboratory uses microarray transcriptome, next generation DNA sequencing including RNA-Seq, T cell epitope mapping, SEREX and other biochemical, immunological approaches and transgene/gene knock-out disease models in order to determine cardiovascular disease (CVD) risk factors, such as hyperlipidemia-, hyperglycemia-, uremia-, endotoxemia, impact the development/progression of vascular inflammation and atherosclerosis.
2. Immunometabolism. Dr. Yang’s laboratory also aims to study how biochemical metabolites in CVD-related pathologies act as either danger signals or homeostatic signals to regulate antigen processing/presentation, vascular immune responses and atherosclerosis.
3. Epigenetic pathology. Dr. Yang’s laboratory also studies how CVD risk factors regulate histone modification process and gene expressions in vascular inflammation and atherosclerosis.

Educational Background

• Fellowship, Immunology and Oncology, Harvard Medical School, 1999
• PhD, Biochemistry and Molecular Biology, University of Montreal, Canada 1994
• MS, Immunology, Chinese National Academy of Medical Sciences and Peking Union Medical University 1982   
• MD, Clinical Medicine, JiangXi Medical University, China 1979

Digital Bibliography

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