Rosario Scalia, MD, PhD
Professor, Cardiovascular Sciences
Professor, Cardiovascular Research Center
Professor, Center for Metabolic Disease Research
Professor, Lemole Center for Integrated Lymphatics and Vascular Research
Professor, Sol Sherry Thrombosis Research Center
Professor, Biomedical Education and Data Science
- Contact Information
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- About Me
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Research Interests
Project 1. We study the role of the microcirculation in the adipose tissue inflammation of the overweight/obese organism to: a) understand how nutrients and excessive calorie intake activates inflammatory signaling cascades in adipose tissue, and b) to find therapeutic targets to averts the metabolic and cardiovascular complications of obesity.
Project 2. Regulation of endothelial function by Calpain. Specifically, we study the impact of calpaan activation on eNOS and endothelial cell adhesion molecule expression levels and functions. We have established the calpain system as an important modulator of endothelial function in insulin resistance and hyperglycemia.
Project 3. We are interested in exploring the main signaling pathways through which physiological aging impairs key function of the vascular endothelium. The overall goal of this research is to find therapeutic targets to offset or delay cardiovascular disease and organ dysfunction in the aging organism.
- Education, Training & Credentials
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Educational Background
- Research Fellowship, Physiology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA, 1999
- Research Fellowship, Pharmacology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA, 1994
- PhD, Vascular Biology, Universities of Catania-Cagliari, Florence, Italy, 1992
- Resident Physician and PhD Student, Department of Pharmacology and Clinical Pharmacology, University of Catania, Italy, 1992
- Internship, Department of Pharmacology and Clinical Pharmacology, University of Catania, Italy, 1987
- MD, University of Catania, Catania, Italy, 1986
Memberships
- American Physiological Society
- Shock Society
- American Association for the Advancement of Science
- American Diabetes Association
- American Heart Association
- The Microcirculatory Society
- Publications
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Digital Bibliography