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The Institute for Clinical Simulation and Patient Safety (ICS) had its genesis in 2002 when the Department of Surgery Residency Program developed a surgical skills laboratory for instruction and objective assessment of the technical abilities of surgical residents.  Following the success of the initial sessions, the scope of the program was expanded and a formal syllabus and curriculum were developed.

In 2004, the Lewis Katz School of Medicine (LKSOM) constructed a designated space for the Institute for Clinical Simulation and Patient Safety. The completion of this facility in July 2005 enabled the centralization of all medical and surgical skills training and simulation activities within the Temple University Health Sciences Campus.

With help from a generous grant from the William Maul Measey foundation, the Institute for Clinical Simulation and Patient Safety relocated in 2009 to the new Medical Education and Research building. In February 2013, construction of the Robotic Surgical Training Center was completed. The creation of the robotic training center enhanced surgical education for practicing surgeons and operating room staff.

The space currently houses both the Clinical Simulation and Standardized Patient programs advancing the integration of simulation services for the training of medical students, PA students, post-baccalaureate students, medical residents and fellows, physicians and the Temple Transport Team.  The institute also provides educational programs for other student learners including those from Temple University College of Public Health and the School of Podiatric Medicine.