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Integrative Pharmacology Core

Scott Rawls, Core Director
Alan Cowan, Co-Investigator
Ronald Tallarida, Co-Investigator
Lynn Kirby, Co-Investigator

The Integrative Pharmacology Core provides the following services:

  • Quantitation of overt rodent behaviors
  • Assessment of analgesia using several different nociceptive stimuli, tolerance, and physical dependence
  • Cellular electrophysiology recordings
  • Measurement of body temperature, GI function, anticonvulsant screening, antipruritic screening
  • In vivo drug dosing methods, ataxia screening
  • Collection of effluents from brain regions of non-anesthetized rats using microdialysis
  • HPLC analysis of glutamate, aspartate and GABA levels
  • Drug-combination analysis and database (PDF)