Mammalian Cell Culture and Neurotropic Viruses
This Core provides mammalian cell culture and virology services to investigators performing biomedical research on AIDS and the nervous system. Services include the preparation of CNS cell cultures, virus propagation, proteomics, biomarkers, and consultative expertise in gene editing. These services promote in uncovering mechanisms involved in the development of nervous system disorders associated with HIV-1 infection.
Basic Science Core I Leadership
Shohreh Amini, PhD, Leader
Ilker Sariyer, DVM, PhD, Co-Leader
Rafal Kaminski, PhD, Co-Leader
George Smith, PhD, Co-Leader
Basic Science Core I Mammalian Cell Culture and Neurotropic Viruses
This section of the Core focuses on the study of HIV-1 infection at the molecular and cellular levels. Services include the purification, characterization, and maintenance of an assortment of central nervous system cells (neurons, astrocytes, oligodendrocytes, microglia, cerebral endothelial cells, progenitor and neural stem cells) and peripheral cells such as macrophages and T-cells.
For additional information, please contact Ilker Sariyer, DVM, PhD.