Mammalian Cell Culture and Neurotropic Viruses

This Core provides mammalian cell culture and virology services to investigators performing biomedical research on AIDS and the nervous system. Services include the preparation of CNS cell cultures, virus propagation, proteomics, biomarkers, and consultative expertise in gene editing. These services promote in uncovering mechanisms involved in the development of nervous system disorders associated with HIV-1 infection.

Basic Science Core I Leadership

Shohreh Amini, PhD, Leader

Ilker Sariyer, DVM, PhD, Co-Leader

Rafal Kaminski, PhD, Co-Leader

George Smith, PhD, Co-Leader

Basic Science Core I Mammalian Cell Culture and Neurotropic Viruses

This section of the Core focuses on the study of HIV-1 infection at the molecular and cellular levels. Services include the purification, characterization, and maintenance of an assortment of central nervous system cells (neurons, astrocytes, oligodendrocytes, microglia, cerebral endothelial cells, progenitor and neural stem cells) and peripheral cells such as macrophages and T-cells.

To request cell samples, please complete the Cell Request Form (PDF) and return to isariyer@temple.edu.

For additional information, please contact Ilker Sariyer, DVM, PhD.