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RFA-HL-14-023 - Clinical Research in the Prevention, Diagnosis, and Treatment of HIV-Related Heart, Lung, and Blood (HLB) Diseases in Adults and Children (R01)

This Funding Opportunity Announcement (FOA) invites clinical research project grant (R01) applications on the prevention, diagnosis, and treatment of HIV-related heart, lung, and/or blood (HLB) diseases in adults and children. Proposed projects may utilize various approaches such as observational studies; quasi-experimental designs; and single-center, pilot trials. Whenever possible, investigators are strongly encouraged to leverage existing infrastructure such as clinical cohorts, biological specimens and imaging banks. The goal of this FOA is to address major scientific gaps in characterizing, preventing, diagnosing, or treating HIV-related HLB diseases and foster multi-disciplinary collaborations among investigators.

The Johns Hopkins NIMH Center for Novel Therapeutics of HIV-associated Cognitive Disorders

The Johns Hopkins NIMH Center is comprised of an interdisciplinary research team who has pooled their talents to study the nature of HIV-associated neurocognitive disorders (HAND). Their aim is to translate discoveries of the pathophysiological mechanisms into novel therapeutics for HAND.

HIV Neurobehavioral Research Center, University of California, San Diego

The mission of the HIV Neurobehavioral Research Center (HNRC) is to increase understanding of how HIV and other diseases affect the human nervous system. The HNRC conducts local, national, and international research devoted to advancing our knowledge of the prevention, diagnosis and treatment of HIV-related diseases as they affect the brain and nervous system, and result in impairment of everyday functioning.

Chronic HIV Infection and Aging in NeuroAIDS (CHAIN) Center, UNMC

The now chronic nature of HIV has been a major advancement in AIDS care. While HIV infected individuals are living longer, damaging effects of HIV persist in the brain and may interact with other neurodegenerative disorders. The CHAIN Center at the University of Nebraska Medical Center will research new ways to diagnose, predict, treat and prevent brain damage induced by HIV via a systems biology approach.

Penn Center for AIDS Research

CFAR's mission is to support, encourage and facilitate research in all areas of HIV/AIDS by (a) facilitating communication and interdisciplinary collaborations through workshops, working groups, strategic planning efforts, and a seminar series covering all topics in the field; (b) support innovative pilot research in HIV/AIDS through developmental pilot grant programs including nonhuman primate-based research; (c) mentoring and support of junior investigators; (d) services and training in support of HIV research through Shared Cores: Clinical, Viral/Molecular, Immunology, Biostatistics & Data Management; Behavioral and Social Sciences; International; Nonhuman Primate.

Mount Sinai Institute for NeuroAIDS Disparities

MSINAD is a collaborative program of the Manhattan HIV Brain Bank and the Center for Multicultural and Community Affairs at the Mount Sinai School of Medicine. The mission of MSINAD is: 1) to stimulate research into NeuroAIDS disorders in minority populations, 2) to provide multidisciplinary education to young scientists interested in pursuing NeuroAIDS research, 3) to encourage entry of scientists from under-represented groups into the field.

International Society for NeuroVirology

The International Society for NeuroVirology is an international forum for researchers and clinician scientists involved in the study of neurovirology. The purpose of the Society is to advance collaboration among scientists in all aspects of neurovirology and related disciplines in order to further knowledge in the area, and promote the clinical application of this knowledge to prevent and treat neuroinflammation and pathophysiology of viral encephalitides.

Journal of Neurovirology

The Journal of NeuroVirology (JNV) provides a unique platform for the publication of high-quality basic science and clinical studies on the molecular biology and pathogenesis of viral infections of the nervous system, and for reporting on the development of novel therapeutic strategies using neurotropic viral vectors. The Journal also emphasizes publication of non-viral infections that affect the central nervous system.