Leveraging data in the Epic EHR, the DCS informatics group can run rudimentary aggregate queries for counts of patients needed for study feasibility work, create small de-identified data sets for preparatory-to-research investigations, or provide PHI on an IRB-approved, as-needed basis to members of the covered entity who require a deeper exploration of data. Rather than requiring multiple iterations of queries, and movement of data from one source to the next to merge data, the Honest-Broker Office will work directly with investigators to refine queries in real time and crosswalk matched patient information from different data sources. When research requires outreach for subject recruitment, the office will create patient lists meeting inclusion criteria and stratified by physician so that signed written approval for patient contact can be created where required. Elements to be included in the data extracts will include clinical data of common need across many research studies including demographics, diagnoses, procedures, laboratory and other ancillary tests and results, medications prescribed or dispensed. Electronic Medical Records can only be extracted and used for clinical research after the research protocol has been approved by the IRB.