In This Section

Research Programs

Molecular, cellular and genetic techniques are being utilized to advance our understanding of microbiology and immunology. The research programs of the department are funded by peer-reviewed grants, including 20 grants from the National Institutes of Health and several grants from industry or foundations. We also collaborate with faculty in other departments in the School of Medicine and the University and colleagues at other national and international institutions. The interdepartmental collaborations and multi-disciplinary programs have increased the breadth of the potential research projects available to graduate students. The graduate faculty maintains close ties with clinical departments and sections, including the Departments of Surgery and Gynecology and Sections of Cardiology and Infectious Diseases.

Current active research areas include the following:

Molecular and Cellular Immunology

  • Molecular and cellular immunology of T and B lymphocytes
  • Molecular aspects of macrophage physiology
  • Signal transduction in immune cells
  • Immune response to neoplasia
  • Dendritic cell biology
  • Cellular and molecular analysis of the role of opioid receptors in the function of cells of the immune system and cannabinoid
  • Microbial immunity
  • T cell apoptosis and immune deviation

Researchers include:

  • Marion Chan
  • Toby Eisenstein
  • Stefania Gallucci
  • Doina Ganea
  • Liselotte Jensen
  • Marc Monestier
  • Tomasz Skorski
  • Alexander Tsygankov

Molecular and Biochemical Microbiology

  • Virulence factors and microbial pathogenesis
  • Host-pathogen interactions
  • Molecular biology of DNA and RNA viruses, including Human Immunodeficiency Virus and Epstein-Barr Virus
  • Plasmid replication

Researchers include:

  • Bettina Buttaro
  • Toby Eisenstein
  • Alexander Tsygankov
    • Çagla Tükel, PhD

Eukaryotic and Prokaryotic Molecular Genetics and Physiology

  • Peptide signaling pathways in Streptococci and Enterococci
  • Cellular and viral oncogenes and their role in cell growth and transformation
  • Molecular modeling and protein structure/function relationships
  • Molecular genetics of the immune response
  • Pheromone inducible conjugative plasmids and horizontal gene transfer

Researchers include:

  • Bettina Buttaro
  • Marc Monestier
  • Tomasz Skorski