In This Section

Manish Gupta, PhD

Instructor, Research

Manish Gupta
Contact Information

Contact Information



About Me

Research Interests

Cardiovascular diseases (CVD) are the leading cause of death globally as suggested by recent scientific studies. A better understanding of various preventative measures for CVD and heart failure is needed. My research is focused on understanding the mechanisms involved in cardiomyopathy and to identify novel strategies to improve heart function by using cell culture, mouse and macaque models.

My current research focuses are:

  • Structure-function analysis of sarcomeric proteins
  • Investigating the role of post translational modifications (Ubiquitination, SUMOylation, phosphorylation) in cellular protein quality control and cardiac function
  • Understanding the role of HIV-1 and antiretroviral drug in cellular toxicity and development of cardiomyopathy
  • CRISPR/CAS9 mediated gene editing
Education, Training & Credentials

Educational Background

  • Fellowship, Cincinnati Children's Hospital Medical Center Heart Institute, Cincinnati, OH
  • Fellowship, University of Cincinnati, Cincinnati, OH
  • PhD, Microbiology, Jawaharlal Nehru University, Lucknow, India
  • MSc, Microbiology, The University of Burdwan, West Bengal, India


  • American Heart Association
  • American Physiological Society
  • International Society for Heart Research
  • International Society for Neuro Virology

Digital Bibliography

View PubMed Publications