In This Section

Lauren Koffman, DO, MS

Assistant Professor, Clinical Neurology

Lauren Koffman
For Patients
About Me

Clinical Interests

  • Intracerebral hemorrhage
  • Aneurysmal subarachnoid hemorrhage
  • Status epilepticus
  • Coma
  • Cerebral edema
  • Brain death

Research Interests

  • Intracerebral hemorrhage
  • Cerebral edema
  • Aneurysmal subarachnoid hemorrhage
Education, Training & Credentials

Educational Background

  • Fellowship, Neurocritical Care, The Johns Hopkins Hospital, Baltimore, MD
  • Residency, Neurology, Cleveland Clinic Foundation, Cleveland, OH
  • DO, Touro College of Osteopathic Medicine, New York, NY
  • MS, Clinical Investigation, Massachusetts General Hospital Institute of Health Professions, Charlestown, MA


  • Neurology
  • Neurocritical Care


  • Neurocritical Care Society
  • Society of Critical Care Medicine
  • American Academy of Neurology
  • American Heart Association

Selected Publications

Peer Reviewed Articles

1. Tavarez T, Roehl K, Koffman L. Nutrition in the neurocritical care unit: A new frontier. Current Treatment Options in Neurology. Accepted awaiting publication.

2. Breit H, Bleck TP, Koffman L. Delirium in the Cardiac Intensive Care Unit. Seminars in Neurology. Accepted pending publication.

3. Abburi N, Sterenstein A, Breit H, Song S, John S, DaSilva I, Koffman L. Description of an association between leukocytosis and clinical outcomes in large hemispheric infarctions. J Stroke Cerebrovasc Dis. 2021 Jan 20;30(4):105614. doi: 10.1016/j.jstrokecerebrovasdis.2021.105614. Epub ahead of print. PMID: 33484981.

4. Radnis C, Qiu S, Jhaveri M, DaSilva I, Szewka A, Koffman L. Radiographic and clinical neurologic manifestations of COVID-19 related hypoxemia. Journal of the Neurological Sciences. 2020 ;418:117119.

5. Forman R, Slota K, Ahmad F, Garg R, John S, DaSilva I, Koffman L. Intracerebral Hemorrhage Outcomes in the Very Elderly. J Stroke Cerebrovasc Dis. 2020;29(5):104695.

6. Koffman L, Rincon F, Gomes J, Singh S, He Y, Ritzl E, Bleck TP, Kaplan PW, Nyquist P. Continuous electroencephalographic monitoring in the intensive care unit: A cross-sectional study. J Intensive Care Med. 2019.

7. Koffman L, Yiu HY, Farrokh S, Lewin J, Geocadin R, Ziai W. Ketamine infusion for refractory status epilepticus: A case report of cardiac arrest. J Clinical Neuroscience. 2018; 47: 149-151.

8. Koffman L, Prayson R, Manno EM. Malignant cerebral edema related to Systemic Lupus Erythematosus. J Neurol Sci. 2016; 364: 180-182.

9. Gomes JA, Selim M, Cotleur A, Hussain MS, Toth G, Koffman L, Asi K, Provencio JJ. Brain iron metabolism and brain injury following subarachnoid hemorrhage: iCeFISH-Pilot (CSF Iron in SAH). Neurocrit Care. 2014; 21:285-293.

10. Taqui A, Koffman L, Hui F, Gomes J, Toth G. Intra-arterial vasodilator therapy in the management of neurovascular complications of pneumococcal meningitis. J Neurol Sci. 2014; 340: 225-229.

Books, Monographs, Chapters

1. Koffman L, Mehrnaz P, Ziai W, Nyquist P. Neuroinfectious Disease. The Practice of Neurocritical Care 2nd Edition. Neurocritical Care Society; 2020: TBD.

2. Chuck C, Koffman L and Bleck TP. The Treatment of Infectious Meningitis and Encephalitis in the NCCU. Neurointensive Care Unit: Clinical Practice and Organization. Nelson S and Nyquist P. Switzerland: Springer; 2019: 233-247.

3. Breit H, Koffman L. Status Epilepticus. Evidence Based Critical Care: A Case Study Approach. Hyzy RC. Switzerland: Springer; 2020: TBD.

4. Ahmad F and Koffman L. Acute Respiratory Distress Syndrome. Textbook of Neuroanesthesia and Neurocritical Care. Prabhakar H. Singapore: Springer, 2018: 367-375.

5. Koffman L, Ziai, Kaplan P. Status Epilepticus. Essentials of Neurointensive Care. Prabhakar H. Oxford, United Kingdom: Oxford University Press, 2017.

6. Koffman L, Koenig M, Geocadin R. Global Hypoxia-Ischemia and Critical Care Seizures. Seizures in Critical Care: A Guide to Diagnosis and Therapeutics, 3E. Varelas P and Claasen J. Zug, Switzerland: Springer, 2017: 227-242.

7. Koffman L and Gomes J. Management of acute demyelinating disorders in the neurocritical care unit. Neurocritical Care. Torbey M. 2nd edition. Cambridge: Cambridge University Press, 2014: 414-420.